30 Grey’s Anatomy episodes sure to make you cry

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(Photo by Frederick M. Brown/Getty Images)
(Photo by Frederick M. Brown/Getty Images) /

20. Season 3, Episode 25, “Didn’t We Almost Have It All?”

Breaking into the Top 20 of Grey’s Anatomy saddest episodes, it’s all about the third season finale. Episode 25, titled “Didn’t We Almost Have It All?” gave us the highly anticipated Burke-Yang wedding. We thought we would finally see Burke and Cristina tie the knot, but it all came crashing down.

Cristina spent much of the episode trying to work through her feelings. She feared the future with Burke. This wasn’t that surprising since she was so focused on her career. Just as she figures out that she does want to be with him, Burke decides to walk away.

This is one of those episodes that will make you angry at first. You’re angry at Burke for Cristina. It makes it even worse that Burke doesn’t even return the next season to clear out his things and gets Mommy Dearest to do it. However, in this moment, Burke may as well tell Cristina that he isn’t happy that she’s chosen him, after all, this time. He makes it clear that it’s too little too late.

So, how can this be one of the saddest episodes of Grey’s Anatomy? It’s at the very end when Cristina struggles to get out of her wedding dress. Screaming at Meredith to cut it out, Cristina breaks down in tears. Once out of the dress, Meredith just holds onto her best friend and makes sure Cristina knows that someone—her person—is there for her.

While it is a beautiful moment between the two friends, it’s also bittersweet and heartbreaking to watch. Cristina is a strong doctor who can often come off as cold, but her emotions were let out completely in this moment and so were ours!