53 Grey’s Anatomy quotes that totally deserve to be framed

ABC’s “Grey’s Anatomy” stars Ellen Pompeo as Meredith Grey. (ABC/Mike Rosenthal)
ABC’s “Grey’s Anatomy” stars Ellen Pompeo as Meredith Grey. (ABC/Mike Rosenthal) /

Grey’s Anatomy is more than a show, it’s a lifestyle.

Ever since its premiere back in 2005, Grey’s Anatomy has defined a generation and to this day still ranks as one of the most popular shows in all of the world.

Characters such as Meredith Grey, Cristina Yang, Richard Webber, Derek Shepherd, Miranda Bailey and so many others have become engraved in pop culture history and are recognized as some of the most beloved characters in TV history for their ground-breaking TV moments and the incredibly impacts they’ve had on the TV landscape and millions of viewers who have tuned in over the years.

In addition to bringing fans countless unforgettable TV moments and some of the most recognizable scenes to have graced the small-screen, Grey’s Anatomy has gifted fans with so many iconic quotes over the years. Quotes not only that defined key moments within the series, but are words that deliver so many truly impactful and powerful moments!

From quotes about love and friendship to messages of self-empowerment, we’ve rounded up 53 amazing Grey’s Anatomy quotes that not only offer up words to live by but deserve to be framed and hung in the Louvre.

53 Best Grey’s Anatomy quotes

1. “Don’t ever date a man who can’t handle your power.” — Meredith Grey

2. “This is your starting line. This is your arena. How well you play? That’s up to you.” — Richard Webber 

3. “At the end of the day, the fact that we show up for each other, in spite of our differences, no matter what we believe, is reason enough to keep believing.” — Miranda Bailey

4. “The future is the home of our deepest fears and our wildest hopes.” — Owen Hunt

5. “Friends are the family we choose.” — Meredith Grey

6. “I Love Everything About You. Even The Things I Don’t Like, I Love.” — Jackson Avery

7. “I’m a human being, I make mistakes. I’m flawed. We all are.” — Derek Shepherd

8. “Oh screw beautiful! I’m brilliant! If you want to appease me, compliment my brain.” — Cristina Yang

9. “You have to go back to the beginning to understand the end.” — Teddy Altman

10. “Sometimes when you think the storm has passed, you realize you were just in the eye of it.” — Meredith Grey 

11. “Don’t let what he wants eclipse what you need. He’s very dreamy, but he’s not the sun. You are.”  — Cristina Yang

Grey's Anatomy Quotes
ABC’s “Grey’s Anatomy” stars James Pickens, Jr. as Richard Webber. (ABC/Mike Rosenthal) /

12. “Sometimes it’s good to be scared. It means you still have something to lose.” — Richard Webber

13. “Deal with your jealousy. Deal with your shortcomings. Don’t put your crap on me.” —  Stephanie Edwards

14. “It’s a beautiful day to save lives.”  — Derek Shepherd

15. “Please, don’t chase me anymore. Unless you’re ready to catch me.” — Callie Torres

16. “We’re friends, real friends. And that means no matter how long it takes, when you finally decide to look back, I’ll still be here.” — Meredith Grey

17. “You’re allowed to want what you want even if it’s not what he wants.” — Richard Webber

18. “Have some fire. Be unstoppable. Be a force of nature. Be better than anyone here and don’t give a damn about what anyone thinks.” — Cristina Yang

19. “Pick me, choose me, love me.” — Meredith Grey

20. “If you aren’t willing to keep looking for light in the darkest of places without stopping, even when it seems impossible, you will never succeed.” — Amelia Shepherd

21. “The only time I don’t feel like a ghost is when you look at me, because when you look at me, you see me. You see me. This is me.” — Owen Hunt

22. “As human beings, sometimes it’s better to stay in the dark, because in the dark there may be fear, but there is also hope.”  — Meredith Grey

23. “Shut up. Dance it out.” -– Cristina Yang

24. “Don’t analyze everything. Just do it.” — Alex Karev

25. “All you can do is be brave enough to get out there. You fought. You loved. You lost. Walk tall.” — Mark Sloan

26. “You are my person. You will always be my person.” — Cristina Yang

27. “You can’t wait for someone to fly underneath you and save your life. I think you have to save yourself.” — Meredith Grey

28. “Just because people do horrible things, it doesn’t always mean they’re horrible people.” — Izzie Stevens

29. “So you fight. Until you can’t fight anymore.” — Amelia Shepherd

30. “Even superhumans need more than a minute to grieve the loss of the person who made them who they are.” — Andrew DeLuca

31. “You were like coming up for fresh air. It’s like I was drowning and you saved me. That’s all I know.” — Derek Shepherd

32. “Some days, the whole world seems upside down. And then, somehow, improbably and when you least expect it, the world rights itself again.” — Meredith Grey

33. “You can have the worst crap in the world happen to you and you can get over it. All you gotta do is survive.” — Alex Karev

34. “I Am Your Chief. Your Boss, Your Commander, Your Overlord, Your Queen. It Means When I Speak, You Listen.” — Jo Wilson

Grey's Anatomy Quotes
ABC’s “Grey’s Anatomy” stars Chandra Wilson as Miranda Bailey. (ABC/Mike Rosenthal) /

35. “Rest is not a dirty word. Rest is not laziness, no matter what you’re told or how many times you’re told it. Rest is love. Rest is peace. Rest is a beautiful model for your children.”  — Miranda Bailey

36. “Failure is inevitable, unavoidable. But failure should never get the last word. You have to hold on to what you want … Never give in, never give up. Stand up. Stand up and take it.” — Meredith Grey

37. “We don’t get unlimited chances to have the things that we want, and this I know. Nothing is worse than missing an opportunity that could have changed your life.”  — Addison Montgomery

38. “Choose someone who would choose you over and over again. — Cormac Hayes

39. “That’s what you do with a secret. You keep it.” — Maggie Pierce

40. “Being aware of your crap and actually overcoming your crap are two very different things” — Cristina Yang

41. “No matter how dark it gets, the sun’s going to rise again.” — Meredith Grey

42. “You can’t be an ass to me all day and then expect me to give you respect.” -– Lexie Grey

43. “I’m busy holding myself together with tape and glue.” — Miranda Bailey

Grey's Anatomy Quotes
ABC’s “Grey’s Anatomy” stars Ellen Pompeo as Meredith Grey. (ABC/Mike Rosenthal) /

44. “Don’t let fear keep you quiet. You have a voice, so use it. Speak up. Raise your hands. Shout your answers. Make yourself heard. Whatever it takes, just find your voice and when you do, fill the damn silence.” — Meredith Grey

45. “The depth of grief that you felt with all the losses is the depth of love.As long as you’re alive you get to feel it.” — Lexie Grey

46. “You don’t give them something to run from. You give them someone to run to.” –- Richard Webber

47. “Sometimes you have to be a shark.” – Lucy Fields

48. “Change … we don’t like it, we fear it. But we can’t stop it from coming. We either adapt to change, or we get left behind. It hurts to grow. Anybody who tells you it doesn’t is lying. But here’s the truth: Sometimes, the more things change, the more they stay the same. And sometimes, oh, sometimes, change is good. Sometimes, change is … everything” — Meredith Grey

49. “This is the way the world changes. Good people, raising babies right” — Catherine Avery

50. “You’re A Survivor. You Survived.” — Jo Wilson

51. “You’re Beautiful. You’re Brilliant. You’re Powerful.” — Jackson Avery

52. “I am woman. Hear me roar.” — Miranda Bailey

53. “Make a plan. Set a goal. Work toward it, but every now and then look around. Drink it in, ’cause this is it. It might all be gone tomorrow.” — Meredith Grey

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